We contacted Procter & Gamble (Pepto-Bismol’s manufacturer). They said Pepto-Bismol products do not contain added wheat or gluten, and that the disintegrant sodium starch glycolate is derived from potato starch. However, they cannot confirm the manufacturing facility is gluten-free, so cross-contact cannot be ruled out. They advise speaking with your healthcare provider if you’re concerned.
What the manufacturer told us
Here’s the statement we received directly from the Pepto-Bismol team at P&G:
Why this can be confusing
Brands can avoid intentionally adding gluten yet still manufacture in facilities where cross-contact is possible. Without facility controls or end-product testing for gluten, companies usually avoid a definitive “gluten-free” claim. Formulas and suppliers can also change over time, so it’s smart to verify the exact product you have.
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Search thousands of medications in AllerGuard. See inactive ingredients, compare brand vs generics, and find labeled gluten-free options fast.

A certified gluten-free alternative
If you prefer a product with a certification, consider Wonderbelly Multi-Symptom (Mixed Berry) — it is certified gluten-free. Always confirm the exact package you’re buying and consult your pharmacist to make sure the product fits your symptoms and medical needs.
Check other meds instantly
Pepto-Bismol is just one example. AllerGuard helps you quickly check whether a medication lists gluten-containing ingredients, view inactive ingredients by manufacturer, and find labeled gluten-free alternatives where available.
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Quick FAQ
Does Pepto-Bismol contain wheat, barley, or rye?
P&G reports no added wheat or gluten ingredients. However, they do not confirm a gluten-free facility, so cross-contact cannot be ruled out.
Is sodium starch glycolate a gluten risk?
P&G states their sodium starch glycolate is produced from potato starch, which is not a gluten source.
Where can I see ingredients for my specific product?
Search the exact product or NDC in AllerGuard to view inactive ingredients, risk flags, and links to official labeling.
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